*** Based on average target enrichment and library preparation kit prices * Based on Illumina HiSeq 2500 System dual flow cell high output mode Total Cost per Sample (excluding bioinformatics) Comparison of WGS and Targeted Sequencing Methods In addition to reagent costs, bioinformatics analysis time and cost shall also be taken into account when considering the suitable methods for your applications. The following table compares WGS and targeted sequencing in terms of sequencing and library preparation reagent costs. Therefore, targeted sequencing has become vital for the continued progress of precision medicine and research. In addition, sequencing an entire genome or exome can be prohibitively expensive in terms of laboratory operations and bioinformatics infrastructure for storing and processing large amounts of data. A focused or targeted approach would be more appropriate for understanding disease progression and guiding therapy selection in clinical setting or massively screening DNA samples in industrial applications. Even with current reduced sequencing costs, a whole genome sequencing approach can be practically used only in specific scenarios such as basic research, population genetics or rare disease detection. One of the challenges the genomics community faces is the continued acquisition of large amounts of sequencing raw data that is yet to be fully and successfully translated and interpreted to help advance research, diagnose and cure diseases on a wider scale. Whole genome sequencing (WGS) and its corresponding whole genome amplification (WGA) method are more suitable for research and discovery types of applications, while targeted sequencing or targeted gene sequencing is essential to many fast-growing clinical and industrial applications where cost and speed are more important. Solid Tumor & FFPE Tissue Genomic Profiling.Tumor Mutational Burden and Comprehensive Cancer Profiling.Respiratory Virus Research During COVID-19.AccuFusion and OmniFusion RNA Gene Fusion.Ultra-high Multiplexing and Performance.CleanPlex DNA/RNA Amplicon Sequencing Menu Toggle.CleanPlex for MGI Plated Single-Indexed PCR Primers.CleanPlex Single-Indexed PCR Primers v2 for Ion Torrent.CleanPlex Plated Unique Dual-Indexed PCR Primers for Illumina. CleanPlex Unique Dual-Indexed PCR Primers for Illumina.CleanPlex Plated Dual-Indexed PCR Primers for Illumina.CleanPlex Dual-Indexed PCR Primers for Illumina.CleanPlex UMI Liquid Biopsy Menu Toggle.CleanPlex for MGI OncoZoom Cancer Hotspot Kit.CleanPlex Respiratory Virus Research Kit.SARS-CoV-2 Emerging Variants Panel Add-on v2.Ready-to-Use Amplicon NGS Kits Menu Toggle.
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